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A devil fruit changes your DNA/lineage factor/Bloodline Elements and even without the original fruit, you can use the fruit eaters DNA to replicate another one . Fruits, from a scientific standpoint, are "devices" to alter DNA.
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Primary theoryLineage Factor is the sole power system of One Piece and Imu's real weapon
Connected contextOther theories and nearby evidence4 links
Related evidence
Arlong stating that Fishmen were originally humans that evolved to gain something akin to the "power of nature"for · Community analysisAt marineford, several people remark to Luffy's showing conquerors haki as reminiscent of Dragon and how "the apple doesn't fall far from the tree". Garp is speaking as if it was a foregone conclusion that Luffy would get it, since Garp himself has it as well.for · Community analysisRayleigh explaining that all living things have the capacity for haki. It's not purely anime magic, they pass it on. But having the ability to do something doesn't mean that you will do it.
The biggest pushback I've had to this idea is usually "Big mom had conquerors haki, and the parents we see weren't combatants, so that can't be true"
And I still fail to understand that logic, because if Luffy lived a peaceful life, he never would've unlocked it. It's a weapon grasped through desperation and danger , but not all strong-willed people who live through dangerous and dire circumstances unlock it, like Kyros or Wyper.for · Community analysisThe discovery and manipulation of lineage factor is "stepping into the realm of God". I don't think this was a random statement. One of God's abilities will be to change his allies lineage factors to become stronger and maybe even possibly change his enemies to be weaker/subservient. Though I made this theory a long time ago , with the reveal of Domi reversi, this may even be what that is.for · Community analysis